Volume 3 : Issue 2, June 2013

Table of Contents, 20 Jun 2013

Research Title/
Graphical Abstract

Article Information /


The Comparisons of Ferritin Level in CSF of Children With Bacterial and Viral Meningitis

Original Research, C6

Rahmati M.B., Moaydi A., Houshmandi M.M., Paktinat M., Hossaini S.

Asian J. Med. Pharm. Res., 3(2): 28-31, 2013.

ABSTRACT: Bacterial meningitis is one of the most potentially serious infections occurring in children. This infection is associated with a high rate of acute complications and risk of long-term morbidity. The diagnosis of meningitis is confirmed by analysis of the CSF. Early and rapid therapeutic approach to patients with presumed bacterial meningitis is essential. In this cross sectional study 45 patients with the diagnostic criteria for meningitis, based on increase of WBC in CSF, as case and 118 subjects as control were assigned. Cases were classified into two groups of bacterial and viral meningitis according to CSF pleocytosis. Control group had sign and symptom of meningitis without CSF pleocytosis and the CSF culture was negative. Blood, CSF culture and measurement of ferritin level in CSF were done by radioimmunoassay method.163 children with impression of meningitis were studied. Glucose level of CSF in control group was higher than cases and ferritin was lower than cases. In bacterial meningitis patients; protein and ferritin levels of CSF were higher than the other groups (p<0.01). In patients with diagnosis of viral meningitis CSF protein level was lower than the others. A significant relationship observed between age and ferritin levels in control (p<0.01) and bacterial meningitis group (p<0.05), there was no correlation in those patients who had viral meningitis. Ferritin level of CSF was significantly different between cases and controls. Results of study indicate that the ferritin level is useful to differentiate bacterial meningitis from viral meningitis.
: Ferritin, CSF, Meningitis, Pleocytosis, Bacterial Meningitis, Viral Meningitis


Comparison Between hydroxyurea alone and Hydroxyurea With Oral Magnesium for Reducing Acute Painful Crisis in Sickle Cell Patients

Original Research, C7

Molavi M , Qasemyzadeh M, Nazemi A, Goodarzi R, Moghtadaie M, Hosaini S, Molavi K.

Asian J. Med. Pharm. Res., 3(2): 32-34, 2013.

ABSTRACT: In the U.S, sickle cell disease is the most common genetic disease identified through the state-mandated newborn screening program. The cardinal clinical feature of sickle cell anemia is pain from vasooclusive episode. The only measure of the intensity of pain is the patient.at the peak levels of pain, the patient is often admitted in hospital.in many past articles, the efficacy of magnesium in reducing painful crisis were studied and they showed the beneficial effects of magnesium.in this article we studied the beneficial effects of adding magnesium to hydroxyurea for reducing painful crisis, reducing admission and increasing HbF and Hb level of SCA patients.method:in this clinical trial study, population is consist of sickle cell anemia or disease by age between 2 month to 18 years old who were referred to Bandar Abbas Pediatric Hospital. The subjects were classified in two groups, group A-patients were treated with hydroxyurea and group B-patients who treated with hydroxyurea and magnesium. CBC, diff, Hb, electrophoresis, liver and kidney markers were checked and after 4week and 6 months later, the patients or parents were asked for pain crisis episodes,admission,admission periods and Hb level and Hb electrophoresis were checked.stathistics were elaborated with the Spss16 software and analyzed with chi-square test.Results:In group B the mean of pain attacks after 6 months were (0.88-1.5) and P-value was 0.46.in group B after 6months,the mean of electrophoresis was (22.5+11.5) and in group A was (17+8.8)and P-value was less than 0.05 that meant the increase of HbF in group B were significant but in other category weren’t any difference between two groups.conclusion:this study indicated that adding magnesium to hydroxyurea in sickle cell anemia patients reduced the episodes of painful crisis within 6 months later and increased the HbF level in electrophoresis within 6 months later but hasn’t any significant difference between two in other variables.
Key words:
   Sickle Cell Anemia, Pain Crisis, Hydroxyurea, Magnesium


Anti-Ulcerative Potential of Egyptian Propolis Against Oxidative Gastric Injury Induced by Indomethacin in Rats

Original Research, C8

Abd El-Hady F.K., El Awdan S.A., Ibrahim A.M.

Asian J. Med. Pharm. Res., 3(2): 35-42, 2013.

ABSTRACT: The anti-ulcerative and antioxidant potentials of Egyptian propolis alcoholic extract as well as its total phenolic and flavonoid contents were evaluated. The content of total phenols and flavonoids of propolis extract were determined by spectrophotometric methods with an FC reagent and by the complexation reaction with aluminium chloride, respectively. The antioxidant activity was examined with 1,1-diphenyl-2-picryl-hydrazyl (DPPH) and superoxide anion radicals scavenging assays. Indomethacin- induced ulcer with or without pylorus ligation was used as the gastric ulcer model in rats. Oxidative stress was evaluated by measuring stomach homogenate levels of GSH, MDA and NO. The effects of the extract on gastric juice volume and acid output were evaluated. The total phenolic and flavonoid contents of propolis extract was 87.65 ± 0.5 mg GAE/g and 113.14 ± 0.86 mg QE/g extract respectively. The in vitro antioxidant activity was demonstrated by its ability to quench free radicals generated by DPPH and superoxide anion radicals, with the IC50 9.97 ± 0.45 and 11.29 ± 0.65 µg/ ml, respectively. Animals pretreated with propolis extract (200 and 400 mg/kg, b.w.) before indomethacin-induced ulcer model resulted in significant decrease in gastric ulcers and improved oxidative balance in gastric mucosal tissues. These findings indicate that Egyptian propolis possesses potent anti-ulcerative and antioxidant activities, corroborating the folk use of propolis preparations, and contributing for its pharmacological validation.
Key words
: Propolis, Anti-ulcer, Gastric ulcer, Indomethacin, Pylorus ligation, Antioxidant, total phenolic and flavonoid contents


Incidence of Mental Disorders in Epileptic Children between 6 to 12 Years Old

Original Research, C9

Mahab M, Ebrahimi Moghadam H, Mirhashemi M.

Asian J. Med. Pharm. Res., 3(2): 43-46, 2013.

ABSTRACT: The purpose of this study was to assess mental disorder in children with epilepsy. The research population included all 6-12 years old children with epilepsy referred to Iran association of epilepsy. These are based on random sampling of 48 children (26 boys and 22 girls) were selected and they were studied by using Children Symptom Inventory (CSI-4). Data were studied and analyzed by descriptive and statistics methods .Results of research showed that 6-12 years old children with epilepsy respectively in Oppositional Defiant disorders, Enuresis, Attention deficit/hyperactivity (lack of focus type), Encopresis, attention deficit/hyperactivity (ADHD type) scored higher than disorders of Specific phobia, Motor and Vocal tic, Obsessive Compulsive, Separation anxiety, Post traumatic stress, Attention deficit/hyperactivity (combined type) and Conduct. And there wasn’t observed any case of disorders of Schizophrenia, Major and Minor depression, Autistic and Asperger. Therefore, physicians should be considering the significant role of mental and emotional factors in addition to physical and tangible issues of patients, too. and by screening and diagnosis and treatment of disorders and also assure the patients with psychiatric intervention and attracting their cooperation in accepting and continuing treatment regimen and reduce their problems which will follow by positive effects of personal, familial, social and economic.
Key words:
Epilepsy, Symptoms, Psychiatric Disorders


Comparison Between ADHD and Normal Children in Mother-Child Relationship

Original Research, C10

Javdan M, Samavi S.A, Sajjadi H, Nikkerdar M.A.

Asian J. Med. Pharm. Res., 3(2): 47-49, 2013.

ABSTRACT: Mother-child relationship can affect children’s personality, and cause, change or reinforce positive or negative behavioral characteristics. How mothers’ treat their children, can have long-term effects on children’s behavior, performance, expectations and finally their personality in the future. The purpose of this study is to examine mother-child relationship in hyperactive children and compare it with normal children. To conduct this research, 34 elementary school boys, aging from 6 to 12 suffering from hyperactivity disorder and normal ones were convenience sampled from the elementary schools of Roudan in 2012. They were given the child-parent questionnaire and also the hyperactivity checklist. Method: this is a qualitative-descriptive and Ex post facto research. The results showed that hyperactivity has a positive correlation with parents’ over supportiveness   and child acceptance; and negative correlation with child rejection and leniency.
Key words:
Hyperactivity, Mother-Child Relation, Child Acceptance, Child Rejection, Leniency



The Relationship between Self-esteem, Mental Health and Quality of Life in Patients with Skin Diseases

Original Research, C11

Garousi Farshi M.T, Pour Sharifi H, Amini Rad M.

Asian J. Med. Pharm. Res., 3(2): 50-54, 2013.

ABSTRACT: The quality of life is a very important issue in health psychology which covers a large part of the public health sense. The health is a common issue in many cultures and a key factor to play social roles. It is not only dependent on the physiological state of the individual, but it also depends on many aspects of his/her mental functioning. The aim of the present study is to investigate the relationship between self-esteem and mental health with the quality of life in patients with skin diseases. This study was performed using correlational method. Pearson correlation and multiple regression methods were used to test research hypotheses. The Persian version of Dermatology Life Quality Index (DLQI), General Health Questionnaire (CHQ-28) and Coopersmith Self-Esteem Inventory were used to evaluate variables. The results showed that there are significant relationships between self-esteem, mental health and quality of life. Accordingly, the research hypotheses were approved. Moreover, the mental health and its various aspects had more contribution in predicting the quality of life in patients with skin diseases compared to self-esteem.
Key words:
Quality of Life, Mental Health, Self-Esteem, Skin Diseases


Neonatal Intestinal Obstruction due to Mesenteric Cyst (Case Report)

Case Report, C12

Goodarzi R. and Houshmandi M.M.

Asian J. Med. Pharm. Res., 3(2): 55-57, 2013.

ABSTRACT: Mesenteric cysts are rare and usually without specific abdominal finding. We report a case of 25- hours- old newborn, who came with the presentations of an intestinal obstruction which was found during operation. It was a mesenteric cyst and atresia of the small bowel causing intestinal obstruction. The cyst with the adjacent loop was resected and intestinal continuity was restored. Mesenteric cyst was compatible with enteric duplication type in microscopic report.
Key words:
Mesenteric Cyst, Neonate, Intestinal Obstruction



Thymoma as a rare Mediastinal Tumor of Childhood (case report)

Case Report, C13

Goodarzi R., Khamesan B. and Houshmandi M.M.

Asian J. Med. Pharm. Res., 3(2): 58-59, 2013.

ABSTRACT: Pediatric mediastinal tumors and cysts are rare disorders that share similarities with adults. Although thymic disorders are rare in infants and children, thymic hyperplasia is the most common process which involves the thymus gland in this population. Thymic enlargement is generally asymptomatic. We report a case of thymic follicular hyperplasia in an infant seven months of age without association with any other disease.
Key words:
Mediastinal Tumor, Thymoma 


Effect of Gibberellic Acid on Phenological Behavior of Abelmoschus Moschatus Medik


Original Research, C14

Dwivedi A., Dwivedi S., and Balakrishnan B.R.

Asian J. Med. Pharm. Res., 3(2): 60-65, 2013.

ABSTRACT: Phenology is the science of recurring events in nature and is the study of the timing of recurrent, biological events, the causes of their timing with regards to abiotic and biotic factors. Phenological events have been greatly influenced by growth hormones in a number of species. Abelmoschus moschatus Medik. Commonly known as Kasturibhendi (Hindi), Musk mallow (English) belongs to family Malvaceae and is medicinally important oil yielding plant. The phenology of the species is greatly influenced by a number of factors like bio and chemical fertilizers. The present paper deals with the effect of GA3 on phonological behavior of the selected species.
Key words:
Abelmoschus Moschatus, Phenology, Gibberellic Acid


Original Research, C


Asian J. Med. Pharm. Res., 3(2): , 2013.

Key words:

Original Research, C

A. M.

J. Life Sci. Biomed., 3(1): , 2013.


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